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In particular, the localization of transporters is specific to the luminal or basolateral membrane of endothelial cells and at astrocytic endfeet of the BBB [181, 183, 185]

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N-Acetyl-L-Cysteine (NAC) is a stable, orally bioavailable form of cysteine — the rate-limiting amino acid in glutathione synthesis — and is the most widely studied precursor in this context